Human chromosome identification by differential staining
نویسندگان
چکیده
منابع مشابه
Staining Techniques for Human Chromosome Identification
An accepted feature of technological development and its associated accumulation of data is that progress occurs in an irregular fashion with 'break throughs' being interspersed by periods of relative inactivity. In the halcyon years of 1955 to 1961, human cytogenetics experienced a revolution which brought the field within the scope of most genetic laboratories. The resulting increase in the v...
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This study was conducted to determine the location of DNA segment with homology to the rat conserved genomic DNA in human chromosomes. The labeled rat genomic DNA was hybridized with normal human (male) metaphases. The study of 74 metaphases after fluorescence in situ hybridization showed 371 twin-spot signals on human chromosomes. Statistical analysis indicated that the specific accumulation o...
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HEN stained with quinacrine o r nitrogen mustard derivatives of quinacrine, certain regions of Drosophila salivary gland chromosomes fluoresce with extraordinary brilliance (VOSA 1970; ELLISON and BARR 1971). Although the biochemical specificity of this reaction is not well understood, the method of quinacrine staining can be used for cytological comparisons of chromosomes among species and wit...
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The success of the Human Genome Project (HGP) has provided a blueprint for the approximately 20,000 gene-encoded proteins potentially active in all of the hundreds of cell types that make up the human body. Yet we still have limited knowledge about a majority of the gene-encoded proteins which are the “building blocks of life” and “cellular machinery”. It is estimated that for nearly half of th...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1971
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197108000-00221